Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 11/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7211355 | 0.96 | ADORA2A (0.48) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7207428 | 0.93 | ADORA2A (0.51) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7207432 | 0.93 | ADORA2A (0.51) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7204932 | 0.92 | ADORA2A (0.51) | ADORA2AADORA3ADORA1ADORA2BMEN1 | |
| SCHEMBL7211364 | 0.91 | ADORA2A (0.45) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7205326 | 0.90 | ADORA2A (0.42) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7568162 | 0.90 | ADORA2A (0.42) | ADORA2AADORA3ADORA1ADORA2B | |
| Formic Acid SCHEMBL7204946 | 0.90 | ADORA2A (0.50) | ADORA2AADORA3ADORA1ADORA2B | |
| Formic Acid SCHEMBL7204951 | 0.90 | ADORA2A (0.50) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7211360 | 0.89 | ADORA2A (0.43) | ADORA2AADORA3ADORA1ADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | claimed |