Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574597 | 0.93 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL7566467 | 0.93 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL7565518 | 0.92 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL7565787 | 0.91 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL7569389 | 0.89 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL7572382 | 0.88 | EDNRA (0.89) | EDNRAEDNRB | |
| SCHEMBL8444966 | 0.88 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL7568270 | 0.87 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL7567461 | 0.86 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL7569655 | 0.86 | EDNRA (0.60) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799206-B1 | ARYL- AND HETARYL-SULFONAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2002-09-11 | — | — | EP | claimed |