Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.54 |
| ▸ | ACE | P12821 | 5/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569584 | 1.00 | MME (0.54) | MMEACEERAP2LNPEPERAP1 | |
| SCHEMBL8450243 | 0.94 | MME (0.57) | MMEACECTSBMMP3CPA1 | |
| SCHEMBL8447122 | 0.94 | MME (0.57) | MMEACECTSBMMP3CPA1 | |
| SCHEMBL8451262 | 0.93 | MME (0.54) | MMEACEERAP2LNPEPERAP1 | |
| SCHEMBL7568368 | 0.93 | MME (0.64) | MMEACEMMP3CPA1ACE2 | |
| SCHEMBL7568928 | 0.93 | MME (0.64) | MMEACEMMP3CPA1ACE2 | |
| SCHEMBL7568362 | 0.93 | MME (0.64) | MMEACEMMP3CPA1ACE2 | |
| SCHEMBL7575158 | 0.91 | MME (0.60) | MMEACEERAP2LNPEPERAP1 | |
| SCHEMBL7575163 | 0.91 | MME (0.60) | MMEACEERAP2LNPEPERAP1 | |
| SCHEMBL8451243 | 0.90 | MME (0.53) | MMEACECTSBMMP3CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |