Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026746 | 0.81 | MEN1 (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL4025325 | 0.78 | KMT2A (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7367929 | 0.78 | HSD17B10 (0.59) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL12437312 | 0.77 | MEN1 (0.60) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL11754243 | 0.77 | MAPT (0.60) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL18029878 | 0.76 | KMT2A (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7562699 | 0.76 | MAPT (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL3497695 | 0.72 | MAPT (0.61) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7562636 | 0.72 | KDM4E (0.61) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL4026473 | 0.72 | KMT2A (0.55) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802179-B1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO LTD (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-5885990-A | FIBRINOLYSIS PROMOTING ACTION; THROMBOLYSIS ACTION | TORII PHARMACEUTICAL CO., LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0802179-A1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO., LTD. (JP) | 1997-10-22 | — | — | EP | disclosed |