Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567010 | 0.85 | ATM (0.42) | PPARGPPARAKMT2ACYP2D6CYP3A4 | |
| SCHEMBL8405171 | 0.85 | ATM (0.42) | PPARGPPARAKMT2ACYP2D6CYP3A4 | |
| SCHEMBL3232420 | 0.85 | ATM (0.42) | PPARGPPARAKMT2ACYP2D6CYP3A4 | |
| SCHEMBL6436887 | 0.84 | GRN (0.36) | PPARGPPARAMEN1KMT2ACYP3A4 | |
| SCHEMBL6436889 | 0.84 | GRN (0.36) | PPARGPPARAMEN1KMT2ACYP3A4 | |
| SCHEMBL3735338 | 0.83 | NPSR1 (0.44) | MEN1KMT2ACYP1A2MAPTPOLB | |
| SCHEMBL8310048 | 0.82 | MEN1 (0.41) | PPARGPPARAMEN1KMT2ACYP2C19 | |
| SCHEMBL8310050 | 0.82 | MEN1 (0.41) | PPARGPPARAMEN1KMT2ACYP2C19 | |
| SCHEMBL730392 | 0.81 | PRSS1 (0.38) | MAPT | |
| SCHEMBL3745677 | 0.81 | PPARA (0.40) | PPARGPPARAMEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746551-B1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | UNIV OHIO STATE RES FOUND (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-1995023139-A1 | OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-08-31 | — | — | WO | disclosed |
| US-5399721-A | Anticoagulant; prepared from aldehyde | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1995-03-21 | — | — | US | disclosed |