Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK2 | Q9HBH9 | 15/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 14/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501589 | 0.87 | MKNK2 (0.61) | MKNK2MKNK1LCK | |
| SCHEMBL7505494 | 0.84 | MKNK2 (0.67) | MKNK2MKNK1LCK | |
| SCHEMBL7022483 | 0.82 | LCK (0.59) | MKNK2MKNK1LCKHPGDALDH1A1 | |
| SCHEMBL7507104 | 0.81 | MKNK2 (0.58) | MKNK2MKNK1LCK | |
| SCHEMBL7019300 | 0.80 | LCK (0.70) | MKNK2MKNK1LCKALDH1A1MAPK1 | |
| SCHEMBL7585824 | 0.79 | MKNK2 (0.57) | MKNK2MKNK1LCK | |
| SCHEMBL7568342 | 0.79 | MKNK2 (0.56) | MKNK2MKNK1LCK | |
| SCHEMBL7571416 | 0.78 | MKNK2 (0.58) | MKNK2MKNK1LCK | |
| SCHEMBL7025681 | 0.77 | MKNK1 (0.87) | MKNK2MKNK1LCK | |
| SCHEMBL7505860 | 0.76 | MKNK1 (0.72) | MKNK2MKNK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |