Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4753921 | 0.99 | ATM (0.55) | ATMSMN1; SMN2LMNATSHRTLR7 | |
| SCHEMBL4755797 | 0.92 | SMN1; SMN2 (0.49) | ATMSMN1; SMN2LMNATSHRTLR7 | |
| SCHEMBL30710541 | 0.85 | TLR7 (0.60) | ATMSMN1; SMN2LMNATSHRTLR7 | |
| SCHEMBL27777013 | 0.82 | TLR7 (0.50) | TLR7ADORA3ADORA1PDE4APDE4B | |
| SCHEMBL2707501 | 0.82 | TLR7 (0.47) | ATMSMN1; SMN2LMNATSHRTLR7 | |
| SCHEMBL3969036 | 0.81 | TLR7 (0.62) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27528655 | 0.81 | CNR1 (0.47) | ATMSMN1; SMN2LMNATSHRTLR7 | |
| SCHEMBL23422154 | 0.80 | TLR7 (0.67) | TLR7PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL3975344 | 0.80 | TLR7 (0.61) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4756005 | 0.80 | TLR7 (0.46) | ATMSMN1; SMN2LMNATSHRTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198232-A4 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2002-07-24 | — | — | EP | claimed |
| EP-1198232-A1 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2000076518-A1 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | claimed |
| CN-1784231-A | 1-amino 1H-imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-06-07 | — | — | CN | disclosed |