Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20796976 | 0.84 | TLR7 (0.46) | TLR8TLR7PDE4APDE4BPDE4C | |
| SCHEMBL6722349 | 0.82 | TLR7 (0.50) | TLR8POLBTLR7PDE4APDE4B | |
| SCHEMBL10587326 | 0.80 | TLR7 (0.48) | TLR8TLR7PDE4APDE4BPDE4C | |
| SCHEMBL1170709 | 0.80 | TLR7 (0.49) | TLR8POLBCXCR4TLR7PDE4D | |
| SCHEMBL3969036 | 0.79 | TLR7 (0.62) | TLR8TLR7PDE4APDE4BPDE4C | |
| SCHEMBL18998178 | 0.78 | KDM4E (0.54) | POLBTLR7CYP1A2CYP2D6TDP1 | |
| SCHEMBL23422154 | 0.78 | TLR7 (0.67) | TLR8TLR7PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL3975344 | 0.78 | TLR7 (0.61) | TLR8TLR7PDE4APDE4BPDE4C | |
| SCHEMBL5356378 | 0.77 | TLR7 (0.52) | TLR8TLR7PDE4APDE4BPDE4C | |
| SCHEMBL16512991 | 0.77 | TLR8 (0.64) | TLR8POLBCXCR4TLR7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198232-A4 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2002-07-24 | — | — | EP | claimed |
| EP-1198232-A1 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2000076518-A1 | UREA SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-12-21 | — | — | WO | claimed |