Sugi Predict

Sugi Predict / Compounds / Naphthoic Acid

Naphthoic Acid

Naphthoic Acid

SCHEMBL7570528

NC(=O)c1ccc(N)cc1.O=C(O)c1cccc2ccccc12

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR4A1 P22736 1/20 0.66
▸ NR4A2 P43354 1/20 0.66
▸ NR4A3 Q92570 1/20 0.66
▸ CDC25B P30305 1/20 0.54
▸ PTPN1 P18031 3/20 0.53
▸ PARP10 Q53GL7 2/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ HPGD P15428 2/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ POLB P06746 2/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ PARP1 P09874 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ BLM P54132 1/20 0.46
▸ PMP22 Q01453 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthoic Acid SCHEMBL7570532 0.90 NR4A1 (0.81) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL8556165 0.83 NR4A1 (0.64) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL3139789 0.83 NR4A1 (0.95) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL27533834 0.83 NR4A1 (0.95) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL20838336 0.81 NR4A1 (0.84) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL27905016 0.81 NR4A1 (0.91) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL30233567 0.81 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL29352220 0.81 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL17258 0.81 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BPTPN1
Naphthoic Acid SCHEMBL28110155 0.81 NR4A1 (1.00) NR4A1NR4A2NR4A3CDC25BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1144399-A3 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP Wyeth (US) 2002-09-11 — — EP disclosed
EP-1144397-A3 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP Wyeth (US) 2002-09-11 — — EP disclosed
EP-1144399-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2001-10-17 — — EP disclosed
EP-1144397-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2001-10-17 — — EP disclosed
EP-1137632-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2001-10-04 — — EP disclosed
EP-1137647-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2001-10-04 — — EP disclosed
WO-2000034261-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 — — WO disclosed
WO-2000034238-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 — — WO disclosed
WO-2000034268-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 — — WO disclosed
WO-2000034258-A2 HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING PHENYLENEDIAMINE GROUP AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 — — WO disclosed