Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461368 | 0.87 | — | — | |
| SCHEMBL7568722 | 0.82 | CYP2D6 (0.42) | — | |
| SCHEMBL8414401 | 0.75 | DPP4 (0.39) | — | |
| Piperazine SCHEMBL8415293 | 0.73 | — | — | |
| SCHEMBL1417525 | 0.72 | — | — | |
| Acetic Acid SCHEMBL27584962 | 0.70 | FFAR3 (0.41) | MEN1KMT2APAOX | |
| SCHEMBL1417711 | 0.70 | — | — | |
| Ethylenediamine SCHEMBL28215986 | 0.69 | PAOX (0.38) | PAOX | |
| Acetic Acid SCHEMBL19893759 | 0.69 | KMT2A (0.39) | MEN1KMT2APAOX | |
| Acetic Acid SCHEMBL11858011 | 0.68 | FFAR3 (0.54) | MEN1KMT2APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934256-B1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | HONEYWELL INT INC (US) | 2002-08-21 | — | — | EP | disclosed |
| EP-0934256-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | AlliedSignal Inc. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998016501-A1 | PROCESS FOR THE PRODUCTION OF CYANOCINNAMAMIDES | ALLIEDSIGNAL INC. (US) | 1998-04-23 | — | — | WO | disclosed |
| US-5654465-A | Process for the production of cyanocinnamamides | ALLIEDSIGNAL INC. (US) | 1997-08-05 | — | — | US | disclosed |