Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571813 | 0.82 | MAPT (0.46) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL7572020 | 0.81 | MAPT (0.42) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL21798649 | 0.79 | MAPT (0.51) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL7564928 | 0.77 | RAD52 (0.47) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL7571817 | 0.77 | RAD52 (0.51) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL21798672 | 0.76 | MAPT (0.47) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL21798673 | 0.75 | MAPT (0.46) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL3811646 | 0.75 | RAD52 (0.48) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL21798679 | 0.73 | MAPT (0.45) | MAPTCYP1A2CYP2C9CYP2C19RAD52 | |
| SCHEMBL14440022 | 0.72 | RAD52 (0.51) | MAPTCYP1A2CYP2C9CYP2C19RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |