Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 17/20 | 0.62 |
| ▸ | FNTB | P49356 | 16/20 | 0.62 |
| ▸ | NRAS | P01111 | 1/20 | 0.56 |
| ▸ | HRAS | P01112 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471961 | 0.88 | FNTA (0.67) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL3501573 | 0.87 | FNTA (0.70) | FNTAPGGT1BFNTBNRASHRAS | |
| Hydrochloric Acid SCHEMBL7657378 | 0.87 | FNTA (0.72) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL31471968 | 0.86 | FNTA (0.82) | FNTAPGGT1BFNTBNRASHRAS | |
| Hydrochloric Acid SCHEMBL7192628 | 0.86 | FNTA (0.70) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL31471963 | 0.86 | FNTA (0.68) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL31471990 | 0.84 | FNTA (0.77) | FNTAPGGT1BFNTBNRASHRAS | |
| Hydrochloric Acid SCHEMBL7664298 | 0.81 | FNTA (0.78) | FNTAPGGT1BFNTBNRASHRAS | |
| SCHEMBL2280782 | 0.77 | FNTA (1.00) | FNTAPGGT1BFNTBNRASHRAS | |
| Hydrochloric Acid SCHEMBL7657393 | 0.76 | FNTA (0.98) | FNTAPGGT1BFNTBNRASHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | FNTA 1/4885PGGT1B 16/4885FNTB 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.