Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7565177 | 0.90 | SMN1; SMN2 (0.60) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL2072196 | 0.89 | KDM4E (0.89) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL26145311 | 0.84 | KDM4E (1.00) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL29936595 | 0.84 | KDM4E (1.00) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL7564891 | 0.82 | SMN1; SMN2 (0.73) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL7567985 | 0.80 | NPC1 (0.68) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL7567000 | 0.78 | ALDH2 (0.72) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL3957582 | 0.78 | SMN1; SMN2 (0.69) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL31236167 | 0.77 | SMN1; SMN2 (0.69) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 | |
| SCHEMBL10001911 | 0.77 | KDM4E (0.68) | KDM4ESMN1; SMN2HSD17B10CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002081491-A2 | NEW GENISTEIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | INSTYTUT FARMACEUTYCZNY (PL) | 2002-10-17 | — | — | WO | disclosed |