Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001439 | 0.82 | KDM4E (0.61) | KDM4EMAPTMAPK1ELANEACHE | |
| SCHEMBL686585 | 0.81 | KDM4E (0.48) | KDM4EMAPTMAPK1ELANETSHR | |
| SCHEMBL8722118 | 0.79 | KDM4E (0.47) | KDM4EMAPTMAPK1ELANEACHE | |
| SCHEMBL11567274 | 0.78 | CA12 (0.45) | KDM4EMCL1KMOTSHRALDH1A1 | |
| SCHEMBL11194302 | 0.78 | MAPT (0.45) | KDM4EMAPTMAPK1FFAR1TSHR | |
| SCHEMBL5678543 | 0.78 | KDM4E (0.46) | KDM4EMAPTMAPK1ELANETSHR | |
| SCHEMBL7551541 | 0.78 | KDM4E (0.46) | KDM4EMAPTMAPK1ELANETSHR | |
| SCHEMBL1551903 | 0.76 | KDM4E (0.44) | KDM4EMAPTMAPK1MCL1ELANE | |
| SCHEMBL7618128 | 0.76 | KDM4E (0.53) | KDM4EMAPTMAPK1ELANEACHE | |
| SCHEMBL27452735 | 0.76 | KDM4E (0.53) | KDM4EMAPTMAPK1TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233045-A2 | Bonding agent for improving the adhesion between rubbers and reinforcing elements | Bayer Aktiengesellschaft (DE) | 2002-08-21 | — | — | EP | disclosed |