SCHEMBL7571252

SCHEMBL7571252

CC(=O)C(C)(C(O)=S)N1C(=O)CCC1=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MT-CO2 P00403 1/20 0.30
ALOX5 P09917 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8629345 0.78
SCHEMBL7209074 0.70 POLB (0.35) POLB
SCHEMBL913291 0.69 POLB (0.34) POLB
SCHEMBL11710143 0.68 POLB (0.32) POLB
SCHEMBL3143318 0.67
SCHEMBL3132415 0.65 CA12 (0.34) POLB
SCHEMBL3516038 0.64
SCHEMBL9285475 0.64 POLB (0.32) POLB
SCHEMBL8351366 0.63 HMGCR (0.30)
SCHEMBL4147046 0.63 GLA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0382781-B1 COMPOSITION FOR TREATING CANCERS CHARACTERIZED BY OVER-EXPRESSION OF THE C-FMS PROTO-ONCOGENE GENETICS INSTITUTE, INC. (US) 1993-09-29 EP claimed
EP-0863401-B1 Analytical test device with liquid-filled blister ROCHE DIAGNOSTICS GMBH (DE) 2002-08-28 EP disclosed
US-6159747-A Analytical test element with a blister filled with liquid ROCHE DIAGNOSTICS GMBH (DE) 2000-12-12 US disclosed
EP-0650054-B1 Process and device for obtaining and detecting immunologically reactive substances from the gas phase SECURETEC GMBH (DE) 2000-08-30 EP disclosed
EP-0863401-A1 Analytical test device with liquid-filled blister Roche Diagnostics GmbH (DE) 1998-09-09 EP disclosed
EP-0650054-A2 Process and device for obtaining and detecting immunologically reactive substances from the gas phase Roche Diagnostics GmbH (DE) 1995-04-26 EP disclosed