Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL757128

N.[Li]CC=C

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30526 0.95
SCHEMBL16460234 0.90
SCHEMBL31310489 0.90
SCHEMBL7135212 0.90
SCHEMBL9542597 0.90
SCHEMBL5648601 0.90
SCHEMBL5983458 0.90
Potassium SCHEMBL9719893 0.90
SCHEMBL7059661 0.90
Water SCHEMBL203056 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103443119-B Cyclosporin-like molecules modified at amino acid 1 and 3 康卓维尔制药公司 2017-09-22 CN claimed
CN-1138582-A heteroatom-comtaining benzocyclopentane-oxazolidinones BAYER AG (DE) 1996-12-25 CN claimed
JP-7070053-A None JP disclosed
CN-115836062-A Compound and medical application thereof 心悦生医股份有限公司 2023-03-21 CN disclosed
US-10611775-B2 Thiophene derivatives TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) 2020-04-07 US disclosed
EP-3558512-A1 METHOD FOR THE CONTINUOUS SYNTHESIS OF A DIENE ELASTOMER WITH LITHIUM AMIDE INITIATOR Compagnie Générale des Etablissements Michelin (FR) 2019-10-30 EP disclosed
EP-3559055-A1 METHOD FOR CONTINUOUS SYNTHESIS OF MODIFIED DIENE ELASTOMER WITH LITHIUM AMIDE INITIATOR Compagnie Générale des Etablissements Michelin (FR) 2019-10-30 EP disclosed
US-20190322684-A1 THIOPHENE DERIVATIVES TIANJIN HEMAY PHARMACEUTICAL CO., LTD. (CN) 2019-10-24 US disclosed
US-10385062-B2 Thiophene derivatives TIANJIN HEMAY BIO-TECH CO., LTD. (CN) 2019-08-20 US disclosed
CN-107496902-A In amino acid/11 and 3 cyclosporins changed similar to molecule 康卓维尔制药公司 2017-12-22 CN disclosed
CN-103443119-B Cyclosporin-like molecules modified at amino acid 1 and 3 康卓维尔制药公司 2017-09-22 CN disclosed
US-5525745-A Intermediates in the preparation of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-06-11 US disclosed
CN-1122803-A Benzoxazolyl- and benzothiazolyloxazolidinones BAYER AG (DE) 1996-05-22 CN disclosed
CN-1119647-A 6-membered nitrogen-containing heteroaryl-oxazolidinones BAYER AG (DE) 1996-04-03 CN disclosed
US-5488183-A Acetylenic cyclohexane triol derivatives WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-01-30 US disclosed
EP-0582481-B1 Preparation of 19-nor-vitamin D compounds WISCONSIN ALUMNI RES FOUND (US) 1995-10-11 EP disclosed
US-5430196-A Preparation of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-07-04 US disclosed
JP-H0770053-A FLUORINATED VITAMIN D DERIVATIVE AND PRODUCTION METHOD THEREFOR NIPPON OIL & FATS CO LTD 1995-03-14 JP disclosed
EP-0582481-A1 Preparation of 19-nor-vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1994-02-09 EP disclosed
WO-1993012123-A1 3-CARBOXY-2-HYDROXY-PROPANE-PHOSPHONIC ACID DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-06-24 WO disclosed