Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985555 | 0.90 | KDM4E (0.49) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL7571218 | 0.85 | CDC25B (0.50) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL6984663 | 0.81 | CACNA1C (0.48) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL7569863 | 0.79 | MAPT (0.46) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL7571121 | 0.78 | KDM4E (0.50) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL7570998 | 0.76 | NSD2 (0.43) | MAPTALDH1A1SLC22A12 | |
| SCHEMBL7577565 | 0.76 | CA12 (0.44) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL7571144 | 0.76 | MAPT (0.47) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL7571031 | 0.75 | MAPT (0.49) | KDM4ESMN1; SMN2KMT2ARAB9AMAPT | |
| SCHEMBL13193177 | 0.75 | CA12 (0.54) | KDM4EKMT2ARAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | KDM4E 3715/4885SMN1; SMN2 4187/4885KMT2A 3687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.