Toluene

Toluene

SCHEMBL7572108

CCOC(=O)C[C@H](O)COCc1ccccc1.Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
MAPK1 P28482 1/20 0.48
NPC1 O15118 1/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.41
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
RGS12 O14924 1/20 0.41
APOBEC3A P31941 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
PPID Q08752 1/20 0.41
TACR1 P25103 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5828117 0.96 CA1 (0.54) CA1CA2CA7CA9MAPK1
SCHEMBL7242401 0.96 CA1 (0.54) CA1CA2CA7CA9MAPK1
SCHEMBL7233591 0.96 CA1 (0.54) CA1CA2CA7CA9MAPK1
SCHEMBL2216473 0.89 CA1 (0.50) CA1CA2CA7CA9MAPK1
SCHEMBL19276019 0.82 NPC1 (0.44) CA1CA2CA7CA9MAPK1
SCHEMBL19255573 0.82 NPC1 (0.44) CA1CA2CA7CA9MAPK1
SCHEMBL3680778 0.81 CA1 (0.57) CA1CA2CA7CA9MAPK1
SCHEMBL7423196 0.81 CA1 (0.57) CA1CA2CA7CA9MAPK1
SCHEMBL3680781 0.81 CA1 (0.57) CA1CA2CA7CA9MAPK1
SCHEMBL8324277 0.81 TACR1 (0.49) CA1CA2CA7CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002096915-A1 PROCESS FOR PRODUCING OPTICALLY PURE Δ - HYDROXY-Β -KETOESTER DERIVATIVES SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2002-12-05 WO disclosed