Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669941 | 0.83 | SLC6A4 (0.50) | TSHR | |
| SCHEMBL9318461 | 0.82 | SLC6A4 (0.49) | TSHR | |
| SCHEMBL29365368 | 0.81 | KDM4E (0.42) | TDP1LMNAHTT | |
| SCHEMBL17070605 | 0.81 | KDM4E (0.42) | TDP1LMNAHTT | |
| SCHEMBL265537 | 0.81 | KDM4E (0.42) | TDP1LMNAHTT | |
| SCHEMBL7122355 | 0.80 | MAPK1 (0.36) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL27266032 | 0.80 | MAPK1 (0.58) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL7110169 | 0.79 | KDM4E (0.41) | TDP1LMNAHTT | |
| SCHEMBL7578688 | 0.79 | MAPK1 (0.37) | MAPK1ALDH1A1TDP1L3MBTL1MEN1 | |
| SCHEMBL17608977 | 0.79 | MAOB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1244531-C | Process for producing 5-bromo-2-fluorobenzoic boric acid | AMERICAN CYANAMID CO (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1403430-A | Process for producing 5-bromo-2-fluorobenzoic boric acid | AMERICAN CYANAMID CO (US) | 2003-03-19 | — | — | CN | disclosed |
| EP-0812847-B1 | Process for the preparation of 5-bromo-2-fluorobenzeneboronic acid | BASF AG (DE) | 2002-09-25 | — | — | EP | disclosed |
| CN-1087743-C | Method for preparing 5-bromo-2-fluorobenzeneboronic acid | AMERICAN CYANAMID CO (US) | 2002-07-17 | — | — | CN | disclosed |
| US-6198008-B1 | PREPARATION OF 5-BROMO-2-FLUOROBENZENEBORONIC ACID, USEFUL AS INTERMEDIATE IN PREPARATION OF FLUOROOLEFIN NON-ESTER PYRETHROID PESTICIDE, WHICH AVOIDS USE OF 2,4-DIBROMOFLUOROBENZENE | AMERICAN CYANAMID COMPANY | 2001-03-06 | — | — | US | disclosed |
| US-5962742-A | Process for the preparation of 5-bromo-2 fluorobenzeneboronic acid | AMERICAN CYANAMID COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| CN-1168887-A | Method for preparing 5-bromo-2-fluorobenzeneboronic acid | AMERICAN CYANAMID CO (US) | 1997-12-31 | — | — | CN | disclosed |
| EP-0812847-A1 | Process for the preparation of 5-bromo-2-fluorobenzeneboronic acid | AMERICAN CYANAMID COMPANY (US) | 1997-12-17 | — | — | EP | disclosed |