Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572293 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1ALDH1A1CHRM3CHRM5 | |
| SCHEMBL7572288 | 1.00 | CHRM2 (0.49) | CHRM2CHRM1ALDH1A1CHRM3CHRM5 | |
| SCHEMBL7571464 | 0.91 | CHRM1 (0.52) | CHRM2CHRM1ALDH1A1CHRM3CHRM5 | |
| SCHEMBL7574861 | 0.89 | CHRM1 (0.45) | CHRM2CHRM1ALDH1A1CHRM3CHRM5 | |
| SCHEMBL7580087 | 0.85 | CHRM3 (0.43) | CHRM2CHRM1ALDH1A1CHRM3CHRM5 | |
| SCHEMBL7578873 | 0.84 | CHRM2 (0.41) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL7573735 | 0.83 | CHRM2 (0.41) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL7571521 | 0.83 | CHRM3 (0.42) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL2493966 | 0.82 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL2478598 | 0.82 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077912-B1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SANOL ARZNEI SCHWARZ GMBH (DE) | 2002-07-03 | — | — | EP | claimed |