SCHEMBL757274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753327	0.91	AR (0.47)	BCHEACHEARHPGDMAOB
	SCHEMBL16921594	0.90	BRD4 (0.58)	BCHEACHEARBRD4HPGD
	SCHEMBL16908927	0.89	BRD4 (0.47)	BCHEACHEBRD4L3MBTL1POLH
	SCHEMBL16921595	0.86	BRD4 (0.44)	BCHEACHEARBRD4MAOB
	SCHEMBL752863	0.86	BRD4 (0.44)	BCHEACHEBRD4L3MBTL1KDM4E
	SCHEMBL753248	0.84	KDM5A (0.43)	BCHEACHEARBRD4MAOB
	SCHEMBL754322	0.84	BRD4 (0.39)	BCHEACHEBRD4HPGDPOLB
	SCHEMBL753097	0.84	BRD4 (0.42)	BCHEACHEARBRD4MAOB
	SCHEMBL752352	0.84	AR (0.40)	BCHEACHEARHPGDMAOB
	SCHEMBL755081	0.83	PLG (0.49)	BCHEACHEARBRD4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.