Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982400 | 0.95 | F2 (0.39) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL7982392 | 0.89 | TRPV1 (0.35) | PTGER1CETPGAAPTGER4 | |
| SCHEMBL7982398 | 0.89 | UTS2R (0.35) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL7986061 | 0.88 | PTGER1 (0.35) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL8047891 | 0.86 | GAA (0.36) | PTGER1KMT2AUTS2RCETPGPR55 | |
| SCHEMBL7515830 | 0.86 | GAA (0.36) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL7982389 | 0.86 | CETP (0.34) | PTGER1KMT2ACETPGAA | |
| SCHEMBL7979267 | 0.85 | PTGER1 (0.34) | PTGER1CETP | |
| SCHEMBL7505090 | 0.85 | PTGER1 (0.38) | MRGPRX4PTGER1CETPGAA | |
| SCHEMBL7505088 | 0.85 | PTGER1 (0.38) | MRGPRX4PTGER1CETPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150978-A4 | CARBAMATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE | BRISTOL MYERS SQUIBB CO (US) | 2002-06-12 | — | — | EP | claimed |
| EP-1150978-A1 | CARBAMATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-07 | — | — | EP | claimed |
| WO-2000044745-A1 | CARBAMATE DERIVATIVES OF DIARYL 1,3,4-OXADIAZOLONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-08-03 | — | — | WO | claimed |
| US-6297241-B1 | TREATMENT OF DISORDERS WHICH ARE RESPONSIVE TO THE OPENING OF THE LARGE CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS. | BRISTOL-MYERS SQUIBB COMPANY | 2001-10-02 | — | — | US | disclosed |
| US-6162817-A | Carbamate derivatives of diaryl 1,3,4-oxadiazolone | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-12-19 | — | — | US | disclosed |