Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 11/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.32 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.32 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3627292 | 0.82 | EPAS1 (0.38) | EPAS1VEGFASLC22A12 | |
| SCHEMBL1054398 | 0.80 | SLC22A12 (0.37) | EPAS1VEGFASLC22A12 | |
| SCHEMBL3958603 | 0.80 | EPAS1 (0.41) | EPAS1PGRSLC22A12 | |
| SCHEMBL13274502 | 0.78 | EPAS1 (0.36) | EPAS1 | |
| SCHEMBL3608428 | 0.78 | EPAS1 (0.36) | EPAS1 | |
| SCHEMBL5728291 | 0.77 | EPAS1 (0.45) | EPAS1VEGFASLC22A12 | |
| SCHEMBL2259279 | 0.76 | AR (0.44) | EPAS1SLC22A12 | |
| SCHEMBL13190916 | 0.75 | EPAS1 (0.35) | EPAS1VEGFA | |
| SCHEMBL4443907 | 0.74 | SLC22A12 (0.40) | SLC22A12 | |
| SCHEMBL8618855 | 0.74 | MAOB (0.45) | EPAS1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |
| EP-1238016-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | Gentian AS (NO) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042368-A1 | SUBSTITUTED PHTHALOCYANINES AND THEIR PRECURSORS | GENTIAN AS (NO) | 2001-06-14 | — | — | WO | disclosed |