Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FOS | P01100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165687 | 0.78 | PPARA (0.55) | KDM4ERAB9ACYSLTR2CYSLTR1ERN1 | |
| SCHEMBL2559891 | 0.77 | KDM4E (0.59) | KDM4ERAB9AERN1ALDH1A1PTGDR2 | |
| SCHEMBL5882010 | 0.77 | KDM4E (0.64) | KDM4ERAB9AERN1ALDH1A1PTGDR2 | |
| SCHEMBL9009618 | 0.77 | KDM4E (0.44) | KDM4ERAB9AALDH1A1TUBB1HSD17B10 | |
| SCHEMBL15331122 | 0.74 | KDM4E (0.55) | KDM4ERAB9AERN1ALDH1A1PTGDR2 | |
| SCHEMBL118322 | 0.74 | KDM4E (0.54) | KDM4ERAB9AERN1ALDH1A1TUBB1 | |
| SCHEMBL20488634 | 0.74 | KDM4E (0.59) | KDM4ERAB9AERN1ALDH1A1TUBB1 | |
| SCHEMBL27500190 | 0.72 | KDM4E (0.58) | KDM4ERAB9ACYSLTR2CYSLTR1ERN1 | |
| SCHEMBL37992 | 0.72 | TDP1 (0.45) | KDM4ERAB9ACYSLTR2CYSLTR1ALDH1A1 | |
| SCHEMBL2560931 | 0.72 | KDM4E (0.55) | KDM4ERAB9AERN1ALDH1A1TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266881-A1 | PROCESS FOR PRODUCING CYCLIC COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |