Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | NOS1 | P29475 | 5/20 | 0.49 |
| ▸ | NOS3 | P29474 | 4/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | ARG2 | P78540 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL30500757 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL578106 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL29449902 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL8040216 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL4952036 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL16894013 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL23521456 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL44977 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL16894014 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 | |
| Arginine SCHEMBL29773893 | 1.00 | OTC (0.54) | OTCDDAH1NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11822 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144859-A1 | DENGUE VACCINE FORMULATION | TAKEDA VACCINES, INC. (US) | 2026-05-28 | — | — | US | claimed |
| EP-3930666-B1 | ORAL CARE PRODUCT | COLGATE PALMOLIVE CO (US) | 2026-05-27 | — | — | EP | claimed |
| US-20260139047-A1 | PHARMACEUTICAL COMPOSITION CONTAINING FUSION PROTEIN | JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) | 2026-05-21 | — | — | US | claimed |
| US-20260139045-A1 | STABILIZED FORMULATIONS CONTAINING ANTI-ANGPTL3 ANTIBODIES | REGENERON PHARMACEUTICALS INC (US) | 2026-05-21 | — | — | US | claimed |
| US-12629420-B2 | CXCR5 antibody formulations | SANOFI (FR) | 2026-05-19 | — | — | US | claimed |
| CN-121674377-B | Preparation method of human blood coagulation factor IX stock solution | 深圳市卫光生物制品股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2026101415-A1 | PHARMACEUTICAL COMPOSITION OF ANTIBODY TO TSLP | Joint Stock Company ‘‘Biocad’’ (RU) | 2026-05-15 | — | — | WO | claimed |
| CN-122004362-A | Tryptophan-added bullfrog feed composition and application thereof | 集美大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4736873-A1 | ANTI-IL-4RALPHA ANTIBODY FORMULATION, PREPARATION METHOD THEREFOR, AND USE THEREOF | Bio-Thera Solutions, Ltd. (CN) | 2026-05-06 | — | — | EP | claimed |
| EP-4735041-A1 | STABILIZER COMPOSITION FOR IMMUNOGENIC COMPOSITIONS, STABILIZED IMMUNOGENIC COMPOSITIONS, METHODS AND APPLICATIONS THEREOF | Biological E Limited (IN) | 2026-05-06 | — | — | EP | claimed |
| EP-0302065-A1 | PHARMACEUTICAL COMPOSITIONS. | EURASIAM LAB (US) | 1989-02-08 | — | — | EP | claimed |
| WO-1988006850-A1 | SALT TASTE ENHANCER | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1988-09-22 | — | — | WO | claimed |
| CN-87103560-A | Pharmaceutical composition | — | 1988-05-18 | — | — | CN | claimed |
| WO-1987005505-A1 | PHARMACEUTICAL COMPOSITIONS | EURASIAM LABORATORIES, INC. (US) | 1987-09-24 | — | — | WO | claimed |
| EP-0217379-A2 | Thrombolytic composition and a process for production thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-08 | — | — | EP | claimed |
| US-4561911-A | CONTAINING AMINO ACID | NIPPON STEEL CORPORATION (JP) | 1985-12-31 | — | — | US | claimed |
| US-4554236-A | Amino acid stabilizers for water soluble diazonium compound condensation products | AMERICAN HOECHST CORPORATION (US) | 1985-11-19 | — | — | US | claimed |
| US-4244943-A | STABILIZATION WITH AMINO ACID, FREEZE DRYING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-13 | — | — | US | claimed |
| US-4035513-A | COSMETICS | SHISEIDO CO., LTD. (JA) | 1977-07-12 | — | — | US | claimed |
| US-3997659-A | PEROXIDE AND PEROXYDISULFATE OR PEROXYDIPHOSPHATE | THE PROCTER & GAMBLE COMPANY (US) | 1976-12-14 | — | — | US | claimed |