Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573071 | 1.00 | EZH2 (0.32) | EZH2GPR84 | |
| SCHEMBL7573485 | 1.00 | EZH2 (0.32) | EZH2GPR84 | |
| SCHEMBL7573070 | 1.00 | EZH2 (0.32) | EZH2GPR84 | |
| SCHEMBL1388997 | 1.00 | EZH2 (0.32) | EZH2GPR84 | |
| SCHEMBL1388995 | 1.00 | EZH2 (0.32) | EZH2GPR84 | |
| Hydrochloric Acid SCHEMBL7578124 | 0.99 | EZH2 (0.31) | EZH2 | |
| Hydrochloric Acid SCHEMBL7577442 | 0.99 | EZH2 (0.31) | EZH2 | |
| Hydrochloric Acid SCHEMBL7578132 | 0.99 | EZH2 (0.31) | EZH2 | |
| SCHEMBL7519503 | 0.97 | EZH2 (0.32) | EZH2GPR84 | |
| SCHEMBL1389156 | 0.97 | EZH2 (0.32) | EZH2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686147-B1 | NOVEL 2,2'-BI-1H-PYRROLE DERIVATIVES WITH IMMUNOSUPPRESSANT ACTIVITY | PHARMACIA ITALIA SPA (IT) | 2002-09-25 | — | — | EP | claimed |
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | claimed |
| EP-0686147-B1 | NOVEL 2,2'-BI-1H-PYRROLE DERIVATIVES WITH IMMUNOSUPPRESSANT ACTIVITY | PHARMACIA ITALIA SPA (IT) | 2002-09-25 | — | — | EP | disclosed |
| EP-1241162-A1 | 2,2'-bi-1H-pyrrole derivatives with immunosuppressant activity | Pharmacia Italia S.p.A. (IT) | 2002-09-18 | — | — | EP | disclosed |
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | disclosed |
| US-5847127-A | Process for the preparation of 2,2'-bipyrrolyl-pyrromethene (prodigiosins) derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| US-5691334-A | IMMUNOMODULATORS FOR SKIN GRAFTS, AUTOIMMUNE AND FOR ORGAN TRANSPLANTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-11-25 | — | — | US | disclosed |