Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.55 |
| ▸ | ACE | P12821 | 10/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7573628 | 1.00 | MME (0.55) | MMEACECPA1ACE2PTGES | |
| SCHEMBL8453091 | 0.95 | MME (0.48) | MMEACECPA1ACE2PTGES | |
| SCHEMBL7568362 | 0.94 | MME (0.64) | MMEACECPA1ACE2GPR34 | |
| SCHEMBL7568368 | 0.94 | MME (0.64) | MMEACECPA1ACE2GPR34 | |
| SCHEMBL7568928 | 0.94 | MME (0.64) | MMEACECPA1ACE2GPR34 | |
| SCHEMBL7567660 | 0.91 | MME (0.58) | MMEACECPA1ACE2GPR34 | |
| SCHEMBL7567652 | 0.91 | MME (0.58) | MMEACECPA1ACE2GPR34 | |
| SCHEMBL7573103 | 0.90 | MME (0.61) | MMEACECPA1ACE2PTGES | |
| SCHEMBL7573107 | 0.90 | MME (0.61) | MMEACECPA1ACE2PTGES | |
| SCHEMBL7570079 | 0.89 | MME (0.58) | MMEACECPA1ACE2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |