SCHEMBL7574466

SCHEMBL7574466

CN1C=C(C(=O)O)N(C)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16774650 0.67
SCHEMBL12283650 0.64
SCHEMBL6712052 0.62
SCHEMBL6563125 0.62
Bicarbonate SCHEMBL28061950 0.61 CA1 (0.33)
SCHEMBL29213684 0.60
Oxalic Acid SCHEMBL28782730 0.59 KDM4E (0.31)
Acetic Acid SCHEMBL26656964 0.59 FFAR3 (0.44)
SCHEMBL20759385 0.58
SCHEMBL28228799 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0999206-B1 Process for producing alpha cyano acetic acid esters BASF AG (DE) 2002-09-18 EP claimed
EP-0985668-B1 Process for preparation of 1,3-dimethyl-imidazolium-4-carboxylate BASF AG (DE) 2001-11-07 EP claimed
US-6175019-B1 BY REACTING 1-METHYLIMIDAZOLE WITH DIMETHYL CARBONATE; COMPOUND USEFUL AS CATALYST FOR PRODUCTION OF ISOPHORONENITRILE (IPN) FROM ISOPHORONE AND HYDROGEN CYANIDE BASF AKTIENGESELLSCHAFT (DE) 2001-01-16 US claimed
US-6130347-A REACTING MONOCHLOROACETIC ESTER WITH HYDROGEN CYANIDE IN BASE PRESENCE; CYANATION BASF AKTIENGESELLSCHAFT (DE) 2000-10-10 US claimed
US-9187412-B2 Process for preparing 3-cyano-3,5,5-trimethylcyclohexanone EVONIK DEGUSSA GMBH (DE) 2015-11-17 US disclosed
US-9085506-B2 Process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine EVONIK DEGUSSA GMBH (DE) 2015-07-21 US disclosed
US-20140114085-A1 PROCESS FOR PREPARING 3-CYANO-3,5,5-TRIMETHYLCYCLOHEXANONE EVONIK DEGUSSA GMBH (DE) 2014-04-24 US disclosed
US-20130253226-A1 PROCESS FOR PREPARING 3-AMINOMETHYL-3,5,5-TRIMETHYLCYCLOHEXYLAMINE EVONIK DEGUSSA GMBH (DE) 2013-09-26 US disclosed
EP-0985668-B1 Process for preparation of 1,3-dimethyl-imidazolium-4-carboxylate BASF AG (DE) 2001-11-07 EP disclosed
US-6175019-B1 BY REACTING 1-METHYLIMIDAZOLE WITH DIMETHYL CARBONATE; COMPOUND USEFUL AS CATALYST FOR PRODUCTION OF ISOPHORONENITRILE (IPN) FROM ISOPHORONE AND HYDROGEN CYANIDE BASF AKTIENGESELLSCHAFT (DE) 2001-01-16 US disclosed
US-6175019-B1 BY REACTING 1-METHYLIMIDAZOLE WITH DIMETHYL CARBONATE; COMPOUND USEFUL AS CATALYST FOR PRODUCTION OF ISOPHORONENITRILE (IPN) FROM ISOPHORONE AND HYDROGEN CYANIDE BASF AKTIENGESELLSCHAFT (DE) 2001-01-16 US disclosed
US-6175019-B1 BY REACTING 1-METHYLIMIDAZOLE WITH DIMETHYL CARBONATE; COMPOUND USEFUL AS CATALYST FOR PRODUCTION OF ISOPHORONENITRILE (IPN) FROM ISOPHORONE AND HYDROGEN CYANIDE BASF AKTIENGESELLSCHAFT (DE) 2001-01-16 US disclosed
US-6130347-A REACTING MONOCHLOROACETIC ESTER WITH HYDROGEN CYANIDE IN BASE PRESENCE; CYANATION BASF AKTIENGESELLSCHAFT (DE) 2000-10-10 US disclosed
EP-0985668-A1 Process for preparation of 1,3-dimethyl-imidazolium-4-carboxylate BASF AKTIENGESELLSCHAFT (DE) 2000-03-15 EP disclosed
US-6022988-A Preparation of 3-cyano-3, 5, 5-trimethylcyclohexanone BASF AKTIENGESELLSCHAFT (DE) 2000-02-08 US disclosed