Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574650 | 0.96 | ADORA2A (0.45) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7202130 | 0.94 | ADORA2A (0.46) | ADORA2A | |
| SCHEMBL7211360 | 0.93 | ADORA2A (0.43) | ADORA2AADORA3ADORA1ADORA2BMEN1 | |
| SCHEMBL7208885 | 0.91 | ADORA2A (0.38) | ADORA2AADORA3ADORA1ADORA2B | |
| Formic Acid SCHEMBL7574645 | 0.90 | ADORA2A (0.49) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7202131 | 0.90 | ADORA2A (0.47) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL7204932 | 0.89 | ADORA2A (0.51) | ADORA2AADORA3ADORA1ADORA2BMEN1 | |
| SCHEMBL7211364 | 0.88 | ADORA2A (0.45) | ADORA2AADORA3ADORA1ADORA2B | |
| SCHEMBL6838968 | 0.88 | ADORA2A (0.44) | ADORA2AADORA3ADORA1ADORA2BMEN1 | |
| SCHEMBL7208763 | 0.87 | CCNA2 (0.39) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | disclosed |