Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18053852 | 0.88 | DHODH (0.50) | DHODHPTGDR2MEN1KMT2ANPC1 | |
| SCHEMBL27285278 | 0.87 | DHODH (0.35) | DHODHPTGDR2LMNAHTTSMN1; SMN2 | |
| SCHEMBL27392041 | 0.86 | DHODH (0.34) | DHODHEPHX2PDE2A | |
| SCHEMBL27295039 | 0.85 | DHODH (0.33) | DHODHEPHX2PDE2A | |
| SCHEMBL8491851 | 0.85 | DHODH (0.47) | DHODHPTGDR2MEN1KMT2ANPC1 | |
| SCHEMBL7575471 | 0.85 | DHODH (0.33) | DHODHEPHX2PDE2A | |
| SCHEMBL7575311 | 0.85 | DHODH (0.33) | DHODHPTGDR2NPC1LMNAHTT | |
| SCHEMBL9116698 | 0.85 | DHODH (0.48) | DHODHCYP3A4CYP2C9CYP2C19EPHX2 | |
| SCHEMBL7573020 | 0.84 | DHODH (0.47) | DHODHPTGDR2MEN1KMT2ANPC1 | |
| SCHEMBL7575001 | 0.83 | DHODH (0.35) | DHODHNPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |
| CN-1039229-C | Herbicides | PHONE POULENC AGRICULTURE LTD (GB) | 1998-07-22 | — | — | CN | claimed |
| CN-1091739-A | Weedicide | PHONE POULENC AGRICULTURE LIMI (GB) | 1994-09-07 | — | — | CN | claimed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| CN-1039229-C | Herbicides | PHONE POULENC AGRICULTURE LTD (GB) | 1998-07-22 | — | — | CN | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| CN-1091739-A | Weedicide | PHONE POULENC AGRICULTURE LIMI (GB) | 1994-09-07 | — | — | CN | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |