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Sugi Predict / Compounds / Benzo[C][1,2,5]Oxadiazole 1-Oxide

Benzo[C][1,2,5]Oxadiazole 1-Oxide

Benzo[C][1,2,5]Oxadiazole 1-Oxide

SCHEMBL7574801

[KH].[O-][n+]1onc2ccccc21

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 1/20 0.47
▸ CA2 P00918 1/20 0.47
▸ CA9 Q16790 1/20 0.47
▸ GRIA2 P42262 1/20 0.41
▸ AHR P35869 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ PKM P14618 1/20 0.39
▸ ABCC1 P33527 1/20 0.37
▸ CATSPER1 Q8NEC5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[C][1,2,5]Oxadiazole 1-Oxide SCHEMBL8492 0.98 CA12 (0.49) CA12CA2CA9GRIA2AHR
Benzo[C][1,2,5]Oxadiazole 1-Oxide SCHEMBL7574797 0.96 CA12 (0.47) CA12CA2CA9GRIA2AHR
SCHEMBL13323566 0.71 MAPT (0.32) CA12CA2CA9
SCHEMBL11017668 0.70 CA12 (0.51) CA12CA2CA9AHRHTT
SCHEMBL11743516 0.70 CA12 (0.51) CA12CA2CA9GRIA2AHR
6-Methylbenzo[C][1,2,5]Oxadiazole1-Oxide SCHEMBL6199005 0.69 NPSR1 (0.47) CA12CA2CA9GRIA2AHR
SCHEMBL1420493 0.69 CA12 (0.56) CA12CA2CA9GRIA2
SCHEMBL4894972 0.69 CA12 (0.56) CA12CA2CA9GRIA2
SCHEMBL17132624 0.69 GRIA2 (0.45) CA12CA2CA9GRIA2AHR
SCHEMBL7747611 0.69 CA12 (0.56) CA12CA2CA9GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020143189-A1 Potassium dinitro benzofuroxane and method of making same SONTI CHIRANJEEVIRAO (US) 2002-10-03 — — US claimed