Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.67 |
| ▸ | ACE | P12821 | 13/20 | 0.67 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575443 | 1.00 | MME (0.67) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL7567514 | 0.91 | MME (0.74) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL7569444 | 0.91 | MME (0.74) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL7569434 | 0.91 | MME (0.74) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8446416 | 0.91 | MME (0.55) | MMEACECPA1ACE2PTPN1 | |
| SCHEMBL7566353 | 0.90 | MME (0.64) | MMEACECPA1ACE2LPAR1 | |
| SCHEMBL7566357 | 0.90 | MME (0.64) | MMEACECPA1ACE2LPAR1 | |
| SCHEMBL7566348 | 0.90 | ACE (0.65) | MMEACECPA1ACE2PTPN2 | |
| SCHEMBL7565990 | 0.88 | MME (0.61) | MMEACECPA1ACE2PTPN2 | |
| SCHEMBL7566002 | 0.88 | MME (0.61) | MMEACECPA1ACE2PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |