Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.46 |
| ▸ | HAT1 | O14929 | 2/20 | 0.31 |
| ▸ | EP300 | Q09472 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757559 | 0.80 | GRM2 (0.58) | GRM2 | |
| SCHEMBL756538 | 0.79 | GRM2 (0.73) | GRM2 | |
| SCHEMBL756539 | 0.79 | GRM2 (0.73) | GRM2 | |
| SCHEMBL759127 | 0.75 | GRM2 (0.58) | GRM2 | |
| SCHEMBL756814 | 0.71 | GRM2 (0.69) | GRM2 | |
| SCHEMBL756852 | 0.71 | GRM2 (0.54) | GRM2 | |
| SCHEMBL757025 | 0.71 | GRM2 (0.86) | GRM2 | |
| SCHEMBL757024 | 0.71 | GRM2 (0.86) | GRM2 | |
| SCHEMBL757530 | 0.68 | GRM2 (0.53) | GRM2 | |
| SCHEMBL2003171 | 0.67 | GRM2 (0.51) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118093-B1 | [1,2,3]TRIAZOLYL SUBSTITUTED QUINOLINES AND COUMARINS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK CANADA INC (CA) | 2012-03-21 | — | — | EP | claimed |