Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 20/20 | 0.51 |
| ▸ | HTR3A | P46098 | 7/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 6/20 | 0.51 |
| ▸ | HTR3B | O95264 | 6/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 6/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7063952 | 0.86 | CHRNA7 (0.52) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7678375 | 0.86 | CHRNA7 (0.52) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7124453 | 0.84 | CHRNA7 (0.57) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7061103 | 0.84 | CHRNA7 (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7061848 | 0.83 | CHRNA7 (0.53) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7696204 | 0.83 | CHRNA7 (0.70) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7063415 | 0.83 | CHRNA7 (0.57) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7157144 | 0.82 | CHRNA7 (0.59) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7063164 | 0.82 | CHRNA7 (0.57) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL7060439 | 0.82 | CHRNA7 (0.56) | CHRNA7HTR3AHTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002015662-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |