SCHEMBL7576

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7721	0.90	LPAR1 (0.48)	LPAR1LPAR2LPAR3FFAR1PPARD
	SCHEMBL7740	0.90	LPAR1 (0.40)	LPAR1LPAR2LPAR3
	SCHEMBL7135	0.88	FFAR1 (0.46)	FFAR1PPARDRXRARXRBRXRG
	SCHEMBL6888	0.85	FFAR1 (0.47)	LPAR1LPAR2LPAR3FFAR1PPARD
	SCHEMBL6706	0.83	LPAR1 (0.41)	LPAR1LPAR2LPAR3
	SCHEMBL6942	0.83	LPAR1 (0.38)	LPAR1LPAR2LPAR3MMP13
	SCHEMBL2086	0.83	LPAR1 (0.38)	LPAR1LPAR2LPAR3MMP13
	SCHEMBL1868	0.82	LPAR1 (0.50)	LPAR1LPAR2LPAR3
	SCHEMBL2264	0.82	LPAR1 (0.50)	LPAR1LPAR2LPAR3
	SCHEMBL18597930	0.81	PTGER1 (0.54)	LPAR1LPAR2LPAR3PTGER1PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.