Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CCR1 | P32246 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 3/20 | 0.41 |
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363096 | 0.84 | KDM4E (0.48) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL16720807 | 0.83 | KDM4E (0.46) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL56776 | 0.80 | KDM4E (0.56) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL30161776 | 0.80 | KDM4E (0.56) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL29466690 | 0.80 | KDM4E (0.56) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL7571214 | 0.80 | KDM4E (0.43) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7572110 | 0.79 | KDM1A (0.40) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL16820308 | 0.79 | KDM4E (0.54) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL20591288 | 0.79 | KDM4E (0.54) | CYP19A1KDM4ELMNACCR1CCR5 | |
| SCHEMBL10767657 | 0.79 | SMN1; SMN2 (0.43) | CYP19A1KDM4ELMNAPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002089799-A2 | USE OF DIHYDROPYRAZOLES TO INCREASE ERYTHROPOIETIN AND VASCULARI ZATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |