Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575872 | 0.84 | CYP19A1 (0.46) | ARCYP19A1LRRK2CYP11B1CYP11B2 | |
| SCHEMBL7572092 | 0.84 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2WNT3AKDM4E | |
| SCHEMBL7137268 | 0.84 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2PDCD1CD274 | |
| SCHEMBL23606173 | 0.82 | AR (0.55) | ARLRRK2ADORA2AADORA1KDM4E | |
| SCHEMBL2775591 | 0.81 | MAP2K4 (0.43) | ARCYP19A1CYP11B1CYP11B2PDCD1 | |
| SCHEMBL18406712 | 0.78 | AR (0.51) | ARLRRK2ADORA2AADORA1CYP11B1 | |
| SCHEMBL7570228 | 0.78 | FFAR1 (0.39) | ARCYP19A1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL7570638 | 0.77 | CYP19A1 (0.49) | ARCYP19A1PDCD1CD274KDM4E | |
| SCHEMBL7569910 | 0.77 | CYP19A1 (0.43) | CYP19A1CYP11B1CYP11B2PDCD1CD274 | |
| SCHEMBL7567116 | 0.77 | NSD2 (0.40) | ARCYP19A1ADORA2APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | AR 4525/4885CYP19A1 589/4885LRRK2 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.