Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690839 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2ZDHHC7ALDH1A1CA14CA12 | |
| SCHEMBL286748 | 0.74 | — | — | |
| SCHEMBL9130100 | 0.74 | — | — | |
| SCHEMBL1512190 | 0.74 | — | — | |
| SCHEMBL13943337 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL5143818 | 0.72 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL16534859 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2ZDHHC7ALDH1A1CA14CA12 | |
| SCHEMBL23028852 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL7583623 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL6559975 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA14CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588372-B1 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL IND CO LTD (JP) | 2002-10-02 | — | — | EP | disclosed |
| EP-0357792-B1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL IND CO LTD (JP) | 1995-06-28 | — | — | EP | disclosed |
| EP-0588372-A1 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5252739-A | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0274379-B1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-5175300-A | Reacting a halo-oxalactic ester with 2-propenal and ammonia; cyclization | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-4973695-A | FROM UNSATURATED ALDEHYDE OR KETONE WITH OXODIESTER | SUGAI CHEMICAL IND. CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0357792-A1 | PROCESS FOR PREPARING PYRIDINE-2,3-DICARBOXYLIC ACID COMPOUNDS | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |
| EP-0274379-A2 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-13 | — | — | EP | disclosed |