SCHEMBL7576769

SCHEMBL7576769

Clc1cccc(-c2ccccc2)c1Cl.Clc1ccccc1-c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.77
CNR2 P34972 2/20 0.47
MAOB P27338 2/20 0.46
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
HSD11B1 P28845 1/20 0.43
P2RX7 Q99572 4/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
ALPL P05186 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489437 0.95 CYP2A6 (0.68) CYP2A6CNR2P2RX7HPGD
SCHEMBL1250242 0.95 CYP2A6 (0.68) CYP2A6CNR2P2RX7HPGD
SCHEMBL27553132 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7HPGDDHODH
SCHEMBL27735081 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7HPGDDHODH
Biphenyl SCHEMBL27846302 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7NPC1RAB9A
SCHEMBL27649310 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7HPGDDHODH
SCHEMBL27448380 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7HPGDDHODH
Ammonia Solution, Strong SCHEMBL28700448 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7HPGDDHODH
Iodide SCHEMBL29162135 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7HPGDDHODH
Methane SCHEMBL27641582 0.93 CYP2A6 (0.65) CYP2A6CNR2P2RX7HPGDDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002012132-A2 PHOTOCATALYTIC DEGRADATION OF ORGANIC COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 2002-02-14 WO disclosed