SCHEMBL7576966

SCHEMBL7576966

c1ccc2c(c1)-c1ccccc1C2CC1c2ccccc2-c2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.64
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
GPR3 P46089 2/20 0.44
ACHE P22303 2/20 0.40
TDO2 P48775 1/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HRH3 Q9Y5N1 1/20 0.40
SLC22A2 O15244 1/20 0.39
SLC22A3 O75751 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5353138 0.82 HTR2A (0.64) HTR2ACA1CA2GPR3ACHE
SCHEMBL4994372 0.81 HTR2A (0.56) HTR2ACA1CA2GPR3ACHE
SCHEMBL1451695 0.81 HTR2A (0.45) HTR2ACA1CA2SLC6A2SLC6A4
SCHEMBL7574105 0.80 HTR2A (0.61) HTR2ACA1CA2GPR3ACHE
SCHEMBL17022715 0.80 HTR2A (0.61) HTR2ACA1CA2GPR3ACHE
SCHEMBL2286468 0.78 HTR2A (0.58) HTR2ACA1CA2GPR3ACHE
SCHEMBL633764 0.78 HTR2A (0.58) HTR2ACA1CA2GPR3ACHE
SCHEMBL261028 0.78 HTR2A (0.58) HTR2ACA1CA2GPR3ACHE
SCHEMBL22664654 0.78 HTR2A (0.58) HTR2ACA1CA2GPR3ACHE
SCHEMBL218397 0.78 HTR2A (0.58) HTR2ACA1CA2GPR3ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512554-A2 Cyclopetadiene type compounds and method for making PHILLIPS PETROLEUM COMPANY (US) 1992-11-11 EP claimed
EP-3214109-B1 POLYCARBONATE RESIN, MOLDED ARTICLE AND OPTICAL FILM MITSUBISHI CHEM CORP (JP) 2024-08-21 EP disclosed
EP-3385300-B1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEM CORP (JP) 2020-12-30 EP disclosed
CN-106461836-B Phase difference film, circularly polarizing plate, and image display device 日东电工株式会社 2020-11-06 CN disclosed
EP-3507268-B1 PROCESS FOR THE SYNTHESIS OF 9,9-BIS(HYDROXYMETHYL)FLUORENE SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-10-21 EP disclosed
CN-106986748-B Oligofluorenediols, oligofluorenediaryl esters, and methods for producing these 三菱化学株式会社 2020-10-09 CN disclosed
US-10754065-B2 Retardation film, circularly-polarizing plate, and image-displaying device NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
US-10732323-B2 Retardation film, circularly-polarizing plate, and image-displaying device NITTO DENKO CORPORATION (JP) 2020-08-04 US disclosed
EP-3303277-B1 PROCESS FOR THE SYNTHESIS OF 9,9-BIS(METHOXYMETHYL)FLUORENE SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-07-29 EP disclosed
CN-106489085-B Phase difference film, circularly polarizing plate, and image display device 日东电工株式会社 2020-06-30 CN disclosed
EP-0920403-A1 PROCESS FOR PREPARING CYCLOPENTADIENYL COMPOUNDS Montell Technology Company bv (NL) 1999-06-09 EP disclosed
WO-1998043931-A1 PROCESS FOR PREPARING CYCLOPENTADIENYL COMPOUNDS MONTELL TECHNOLOGY COMPANY B.V. (NL) 1998-10-08 WO disclosed
US-5786495-A HIGH MOLECULAR WEIGHT ATACTIC POLYPROPYLENE POLYMERIZATION CATALYST MONTELL TECHNOLOGY COMPANY BV (NL) 1998-07-28 US disclosed
EP-0832866-A2 Process for the preparation of methylene-bridged biscyclopentadienyl compounds TARGOR GmbH (DE) 1998-04-01 EP disclosed
US-5571880-A CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1996-11-05 US disclosed
EP-0729968-A1 Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins Montell Technology Company bv (NL) 1996-09-04 EP disclosed
EP-0666267-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-08-09 EP disclosed
US-5149857-A Reacting alkylthiophenyl carbonates with dialkyl sulfates MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-09-22 US disclosed
US-5101059-A Xanthene compounds RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-03-31 US disclosed
WO-1991008190-A1 AMINO ACID PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO disclosed