Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 19/20 | 0.84 |
| ▸ | HTR2A | P28223 | 9/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216958 | 0.91 | CCR3 (1.00) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6331257 | 0.87 | CCR3 (0.73) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6330505 | 0.86 | CCR3 (0.78) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6339155 | 0.85 | CCR3 (0.87) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6331972 | 0.83 | CCR3 (0.84) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6328544 | 0.83 | HTR2A (1.00) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6330944 | 0.83 | CCR3 (1.00) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6339192 | 0.82 | CCR3 (0.83) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6333106 | 0.82 | CCR3 (0.67) | CCR3HTR2ACYP2D6 | |
| SCHEMBL6331000 | 0.82 | CCR3 (0.73) | CCR3HTR2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156807-A4 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARM CO (US) | 2002-04-03 | — | — | EP | disclosed |
| EP-1156807-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000035449-A1 | N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |