Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712837 | 0.85 | CYP3A4 (0.39) | TSHRMAPTCYP3A4TDP1CACNA1B | |
| SCHEMBL19155610 | 0.83 | FUCA1 (0.33) | TSHRMAPTCYP3A4TDP1GAA | |
| SCHEMBL20253754 | 0.79 | TSHR (0.33) | TSHRMAPTCYP3A4TDP1GAA | |
| SCHEMBL20253599 | 0.79 | ERN1 (0.35) | TSHRMAPTCYP3A4TDP1GAA | |
| Hydrochloric Acid SCHEMBL11188101 | 0.78 | SUCNR1 (0.46) | TSHRMAPTCYP3A4TDP1CACNA1B | |
| SCHEMBL7575246 | 0.77 | CYP3A4 (0.34) | TSHRMAPTCYP3A4TDP1CACNA1B | |
| SCHEMBL9436542 | 0.77 | CYP3A4 (0.34) | TSHRMAPTCYP3A4TDP1CACNA1B | |
| SCHEMBL2175986 | 0.76 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL20253786 | 0.76 | CYP3A4 (0.36) | TSHRMAPTCYP3A4TDP1CACNA1B | |
| SCHEMBL20253751 | 0.76 | CYP3A4 (0.36) | TSHRMAPTCYP3A4TDP1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101898993-A | Preparation method of 4-hydroxyl ketopyrrolidine-2-acetamide | YUAN DI | 2010-12-01 | — | — | CN | disclosed |
| US-20020042055-A1 | Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions | MAXYGEN, INC. | 2002-04-11 | — | — | US | disclosed |
| WO-2001046476-A1 | ALTERATION OF HYDROLASE GENES AND SCREENING OF THE RESULTING LIBRARIES FOR THE ABILITY TO CATALYZE SPECIFIC REACTIONS | MAXYGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| US-5721018-A | Method for producing multilayer coatings | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-02-24 | — | — | US | disclosed |
| US-5395659-A | Cationic polymers, clear coats, automobiles | HERBERTS GMBH (DE) | 1995-03-07 | — | — | US | disclosed |
| US-4909915-A | Water dilutable poly (meth)acrylate containing ionic groups | HERBERTS GESELLSCHAFT MIT BESCHRANKTER (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4865705-A | Non-auto crosslinking binder combination, aqueous coating compound containing the same and its use | HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-12 | — | — | US | disclosed |
| CN-87105631-A | Non-auto crosslinking binder combination and the aqueous coating and the application thereof that contain this mixture | — | 1988-03-02 | — | — | CN | disclosed |
| CN-87105636-A | The non-self-crosslinking adhesive composition contains the water japanning liquid and the application thereof of this binder composition | — | 1988-03-02 | — | — | CN | disclosed |