Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7584557 | 1.00 | EZH2 (0.30) | EZH2 | |
| SCHEMBL7574259 | 1.00 | EZH2 (0.30) | EZH2 | |
| SCHEMBL7575714 | 1.00 | EZH2 (0.30) | EZH2 | |
| SCHEMBL7577651 | 1.00 | EZH2 (0.30) | EZH2 | |
| SCHEMBL7577658 | 1.00 | EZH2 (0.30) | EZH2 | |
| Hydrochloric Acid SCHEMBL7585992 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL7577372 | 0.99 | — | — | |
| Hydrochloric Acid SCHEMBL7583907 | 0.99 | — | — | |
| SCHEMBL7583838 | 0.93 | — | — | |
| SCHEMBL7573566 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686147-B1 | NOVEL 2,2'-BI-1H-PYRROLE DERIVATIVES WITH IMMUNOSUPPRESSANT ACTIVITY | PHARMACIA ITALIA SPA (IT) | 2002-09-25 | — | — | EP | claimed |
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | claimed |
| EP-0686147-B1 | NOVEL 2,2'-BI-1H-PYRROLE DERIVATIVES WITH IMMUNOSUPPRESSANT ACTIVITY | PHARMACIA ITALIA SPA (IT) | 2002-09-25 | — | — | EP | disclosed |
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | disclosed |
| US-5847127-A | Process for the preparation of 2,2'-bipyrrolyl-pyrromethene (prodigiosins) derivatives | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| US-5691334-A | IMMUNOMODULATORS FOR SKIN GRAFTS, AUTOIMMUNE AND FOR ORGAN TRANSPLANTS | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-11-25 | — | — | US | disclosed |