Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 4/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3125883 | 0.77 | MAPT (0.58) | MAPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL3143191 | 0.76 | MAPT (0.52) | MAPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL3138342 | 0.76 | MAPT (0.52) | MAPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL3128992 | 0.75 | SCN4A (0.74) | MAPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL3160320 | 0.73 | MAPK14 (0.42) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL13363877 | 0.73 | ERBB2 (0.39) | MAPTMEN1KMT2AGAANPC1 | |
| SCHEMBL3138716 | 0.72 | MAPT (0.56) | MAPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL3131849 | 0.71 | KMT2A (0.51) | MAPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL3135386 | 0.71 | MAPT (0.52) | MAPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL28251671 | 0.71 | NPC1 (0.74) | MAPTL3MBTL1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265866-A2 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | Euro-Celtique S.A. (LU) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001068612-A2 | ARYL SUBSTITUTED PYRIDINES, PYRIMIDINES, PYRAZINES AND TRIAZINES AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2001-09-20 | — | — | WO | disclosed |