Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.71 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13624709 | 0.78 | PTPN1 (0.61) | PTPN1PARK7NSD2HKDC1ALDH1A1 | |
| SCHEMBL30252636 | 0.77 | PTPN1 (0.62) | PTPN1PARK7NSD2HKDC1ALDH1A1 | |
| SCHEMBL13611379 | 0.75 | PTPN1 (0.75) | PTPN1PARK7NSD2HKDC1ALDH1A1 | |
| SCHEMBL5595788 | 0.74 | PTPN1 (0.68) | PTPN1NSD2HKDC1ALDH1A1PTPRC | |
| SCHEMBL4196479 | 0.72 | MEN1 (0.49) | PTPN1PARK7NSD2HKDC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4120194 | 0.70 | MEN1 (0.47) | PTPN1PARK7NSD2HKDC1ALDH1A1 | |
| SCHEMBL8022619 | 0.70 | TDP1 (0.47) | MAOATDP1RXRA | |
| SCHEMBL14307231 | 0.70 | PTPN1 (0.77) | PTPN1NSD2ALDH1A1APAF1 | |
| SCHEMBL9628184 | 0.70 | PTPN1 (0.77) | PTPN1NSD2ALDH1A1APAF1 | |
| SCHEMBL14307222 | 0.70 | PTPN1 (0.77) | PTPN1NSD2ALDH1A1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025107-B1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LTD (GB) | 2002-08-07 | — | — | EP | disclosed |
| US-6303673-B1 | FOR OPTICAL ELEMENTS | JAMES ROBINSON LIMITED (GB) | 2001-10-16 | — | — | US | disclosed |
| EP-1025107-A1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020630-A1 | PHOTOCHROMIC COMPOUNDS | JAMES ROBINSON LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |