Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574704 | 0.97 | ESR1 (0.43) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7573082 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7573182 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7572730 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7573279 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7581461 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7571722 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7579545 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7572221 | 0.96 | ESR1 (0.42) | ESR1ESR2MAPTRAB9AKMT2A | |
| SCHEMBL7578891 | 0.95 | ESR1 (0.49) | ESR1ESR2MAPTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731084-B1 | Photocrosslinkable naphthyl derivatives | ROLIC AG (CH) | 2002-09-25 | — | — | EP | disclosed |
| EP-0731084-A2 | Photocrosslinkable naphthyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-11 | — | — | EP | disclosed |