Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL7580730

C=C(C)C(=O)OC.C=CC(=O)OCC.C=CC(=O)OCCCCCC(C)C

nearest known ligand 0.47

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.47
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.44
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 1/20 0.34
THRB P10828 2/20 0.34
ABCB1 P08183 1/20 0.32
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
ESR1 P03372 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26628042 0.95 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
Methacrylic Acid SCHEMBL9709007 0.91 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
Acrylic Acid SCHEMBL11783796 0.91 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
Acrylic Acid Ethyl Ester SCHEMBL7225855 0.88 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7912783 0.88 TSHR (0.45) TSHRALDH1A1CYP3A4HPGDTP53
Acrylic Acid Ethyl Ester SCHEMBL7531396 0.87 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29004140 0.87 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL31216393 0.87 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
Acrylonitrile SCHEMBL26970015 0.86 TSHR (0.48) TSHRALDH1A1CYP3A4HPGDABCB1
Acrylic Acid Ethyl Ester SCHEMBL11118297 0.86 TSHR (0.38) TSHRALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0904554-B1 ULTRA-FLEXIBLE RETROREFLECTIVE SHEETING WITH COATED BACK SURFACE MINNESOTA MINING & MFG (US) 2002-09-25 EP disclosed
EP-0891568-B1 Structured retroreflective sheeting having a rivet-like connection MINNESOTA MINING & MFG (US) 2001-06-13 EP disclosed
EP-0904554-A1 ULTRA-FLEXIBLE RETROREFLECTIVE SHEETING WITH COATED BACK SURFACE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-03-31 EP disclosed
EP-0891568-A1 STRUCTURED RETROREFLECTIVE SHEETING HAVING A RIVET-LIKE CONNECTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-01-20 EP disclosed
WO-1997037249-A9 ULTRA-FLEXIBLE RETROREFLECTIVE SHEETING WITH COATED BACK SURFACE 1999-01-14 WO disclosed
US-5784197-A Ultra-flexible retroreflective sheeting with coated back surface MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-07-21 US disclosed
US-5754338-A Structured retroreflective sheeting having a rivet-like connection MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-05-19 US disclosed
WO-1997037249-A1 ULTRA-FLEXIBLE RETROREFLECTIVE SHEETING WITH COATED BACK SURFACE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-10-09 WO disclosed
WO-1997037251-A1 STRUCTURED RETROREFLECTIVE SHEETING HAVING A RIVET-LIKE CONNECTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-10-09 WO disclosed