Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TYMP | P19971 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | UPP1 | Q16831 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6542297 | 0.83 | KDM4E (0.41) | KDM4EPKMALDH1A1HPGDHSD17B10 | |
| SCHEMBL5182348 | 0.73 | UPP1 (0.64) | KDM4EPKMALDH1A1HPGDHSD17B10 | |
| SCHEMBL6543180 | 0.73 | KDM4E (0.40) | KDM4EPKMALDH1A1HPGDHSD17B10 | |
| SCHEMBL15375288 | 0.70 | TYMP (0.62) | KDM4EPKMALDH1A1HPGDHSD17B10 | |
| SCHEMBL4650112 | 0.68 | UPP1 (0.39) | ALDH1A1HSD17B10UPP1CYP1A2CYP2C19 | |
| SCHEMBL8941878 | 0.68 | UPP1 (0.61) | KDM4EALDH1A1HPGDHSD17B10TYMP | |
| SCHEMBL6543058 | 0.66 | UPP1 (0.51) | KDM4EPKMALDH1A1HPGDHSD17B10 | |
| SCHEMBL6625526 | 0.65 | UPP1 (0.66) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL12432434 | 0.62 | — | — | |
| SCHEMBL11350793 | 0.62 | MAPT (0.61) | KDM4EPKMALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218449-A2 | MONOAZO DYESTUFFS USEFUL FOR COLOUR FILTERS AND INK JET PRINTING | Avecia Limited (GB) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021714-A2 | MONOAZO DYESTUFFS USEFUL FOR COLOUR FILTERS AND INK JET PRINTING | AVECIA LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |