Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 3/20 | 1.00 |
| ▸ | APBA1 | Q02410 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | CCR6 | P51684 | 2/20 | 0.74 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.74 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.74 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.74 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | RGS4 | P49798 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7582309 | 1.00 | MAPT (1.00) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7582161 | 0.93 | MAPT (0.86) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7580794 | 0.88 | MAPT (0.79) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7582395 | 0.86 | MAPT (0.75) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7582505 | 0.85 | MAPT (1.00) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7580750 | 0.85 | MAPT (1.00) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7580868 | 0.85 | MAPT (0.89) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7589474 | 0.85 | MAPT (0.76) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7584263 | 0.82 | MAPT (0.69) | MAPTNPSR1LMNACACNA1BAPBA1 | |
| SCHEMBL7582617 | 0.77 | MAPT (0.86) | MAPTNPSR1LMNACACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476061-B1 | Fungicides containing pyrrolidones as their active agents | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-05 | — | — | US | claimed |
| EP-1133229-B1 | FUNGICIDES CONTAINING PYRROLIDONES AS THEIR ACTIVE AGENTS | BASF AG (DE) | 2002-10-09 | — | — | EP | claimed |
| US-6476061-B1 | Fungicides containing pyrrolidones as their active agents | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-05 | — | — | US | disclosed |
| EP-1133229-B1 | FUNGICIDES CONTAINING PYRROLIDONES AS THEIR ACTIVE AGENTS | BASF AG (DE) | 2002-10-09 | — | — | EP | disclosed |