Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272244 | 0.79 | MAPT (0.66) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL8404431 | 0.79 | MAPT (0.66) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL12121763 | 0.78 | MAPT (0.63) | MAPTALDH1A1HTTKDM4ENOS1 | |
| Hydrochloric Acid SCHEMBL9534267 | 0.78 | MAPT (0.63) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL2919847 | 0.76 | MAPT (0.61) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL23083828 | 0.76 | MAPT (0.61) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL2268804 | 0.76 | MAPT (0.61) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL16061625 | 0.76 | MAPT (0.61) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL2271171 | 0.76 | MAPT (0.61) | MAPTALDH1A1HTTKDM4ENOS1 | |
| SCHEMBL20681042 | 0.76 | MAPT (0.61) | MAPTALDH1A1HTTKDM4ENOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904769-B1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | OREAL (FR) | 2002-09-25 | — | — | EP | claimed |
| US-6027538-A | OXIDATION DYEING OF KERATINOUS FIBERS CONTAINING AT LEAST ONE COUPLER SELECTED FROM INDAZOLEAMINE DERIVATIVES AND AT LEAST ONE OXIDATION BASE; POWERFUL, NOT VERY SELECTIVE HAIR DYES WHICH ARE CAPABLE OF GENERATING INTENSE COLOR | L'OREAL S.A. (FR) | 2000-02-22 | — | — | US | disclosed |